Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 3/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CDC25C | P30307 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711982 | 0.84 | LMNA (0.48) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL9712004 | 0.84 | ERN1 (0.36) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL22083867 | 0.81 | S100A4 (0.39) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL10364821 | 0.81 | LMNA (0.44) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL14279407 | 0.81 | LMNA (0.44) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL7760109 | 0.81 | PTGS2 (0.47) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL29594315 | 0.79 | S100A4 (0.50) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL10035839 | 0.79 | S100A4 (0.50) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8595709 | 0.78 | PTGS2 (0.51) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL10285192 | 0.78 | LMNA (0.41) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570780-B1 | Chloroethylsulphonylbenzaldehydes | BASF AG (DE) | 1996-03-06 | — | — | EP | claimed |
| EP-0570780-A1 | Chloroethylsulphonylbenzaldehydes | BASF Aktiengesellschaft (DE) | 1993-11-24 | — | — | EP | claimed |
| EP-0309839-B1 | PROCESS FOR THE PREPARATION OF OXYETHYL MERCAPTOBENZALDEHYDES, AND THEIR OXIDATION PRODUCTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-04 | — | — | EP | claimed |
| JP-6032772-A | — | — | None | — | — | JP | disclosed |
| EP-2788345-B1 | DERIVATIVES OF 4-HYDROXY-1,2,3,4-TETRAHYDRONAPHTALEN-1-YL UREA AND THEIR USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT | CHIESI FARM SPA (IT) | 2020-06-10 | — | — | EP | disclosed |
| US-9458154-B2 | Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-10-04 | — | — | US | disclosed |
| CN-103987708-B | The derivant of 4-hydroxyl-1,2,3,4-naphthane-1-base urea and the purposes in treatment of respiratory diseases thereof | 奇斯药制品公司 | 2016-06-22 | — | — | CN | disclosed |
| US-20150057273-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-02-26 | — | — | US | disclosed |
| EP-2788345-A1 | DERIVATIVES OF 4-HYDROXY-1,2,3,4-TETRAHYDRONAPHTALEN-1-YL UREA AND THEIR USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT | Chiesi Farmaceutici S.p.A. (IT) | 2014-10-15 | — | — | EP | disclosed |
| CN-103987708-A | Derivatives of 4-hydroxy-1,2,3,4-tetrahydronaphtalen-1-yl urea and uses thereof in the treatment of diseases of the respiratory tract and other diseases | CHIESI FARMA SPA | 2014-08-13 | — | — | CN | disclosed |
| EP-2303267-B1 | POLYMORPHIC FORM OF A [1, 2, 4] TRIAZOLO [4, 3-A]PYRIDINE DERIVATIVE FOR TREATING INFLAMMATORY DISEASES | PFIZER LTD (GB) | 2013-07-03 | — | — | EP | disclosed |
| US-20110003848-A1 | Polymorphic Form Of A [1,2,4]Triazole[4,3-A] Pyridine Derivative For Treating Inflammatory Diseases | PFIZER LIMITED (GB) | 2011-01-06 | — | — | US | disclosed |
| US-20110003848-A1 | Polymorphic Form Of A [1,2,4]Triazole[4,3-A] Pyridine Derivative For Treating Inflammatory Diseases | PFIZER LIMITED (GB) | 2011-01-06 | — | — | US | disclosed |
| US-20110003848-A1 | Polymorphic Form Of A [1,2,4]Triazole[4,3-A] Pyridine Derivative For Treating Inflammatory Diseases | PFIZER LIMITED (GB) | 2011-01-06 | — | — | US | disclosed |
| WO-2009098612-A2 | POLYMORPHIC FORM OF A [1, 2, 4] TRIAZOLO [4, 3-A] PYRIDINE DERIVATIVE FOR TREATING INFLAMMATORY DISEASES | PFIZER LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |
| EP-0570780-B1 | Chloroethylsulphonylbenzaldehydes | BASF AG (DE) | 1996-03-06 | — | — | EP | disclosed |
| US-5493057-A | INTERMEDIATES FOR REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| JP-H0632772-A | CHLOROETHYLSULFONYLBENZALDEHYDE | BASF AG | 1994-02-08 | — | — | JP | disclosed |
| EP-0570780-A1 | Chloroethylsulphonylbenzaldehydes | BASF Aktiengesellschaft (DE) | 1993-11-24 | — | — | EP | disclosed |
| EP-0309839-A1 | Process for the preparation of oxyethyl mercaptobenzaldehydes, and their oxidation products | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003848-A1 | Polymorphic Form Of A [1,2,4]Triazole[4,3-A] Pyridine Derivative For Treating Inflammatory Diseases | CYP1B1, UBE2V1, CYP4B1 | MEN1 4868/4885LMNA 3780/4885THRB 495/4885 |
| US-20150057273-A1 | KINASE INHIBITORS | MAPK1, MAP3K1, MAPK4 | MEN1 4726/4885LMNA 3345/4885THRB 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.