SCHEMBL7763428

SCHEMBL7763428

C=Cc1ccc(C(C=C)OCCCC)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
TAS1R3 Q7RTX0 2/20 0.37
TAS1R1 Q7RTX1 2/20 0.37
ALDH1A1 P00352 1/20 0.35
AHR P35869 1/20 0.33
PLA2G4B P0C869 1/20 0.32
GAA P10253 1/20 0.32
SLC2A1 P11166 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.31
CASR P41180 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6540266 0.83 LTA4H (0.41) CASRTP53TSHR
SCHEMBL27466473 0.81 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL27823090 0.79 LTA4H (0.41) PLA2G4BCASRTP53TSHR
SCHEMBL29690459 0.78 ALDH1A1 (0.38) ALDH1A1PLA2G4BCASRTSHR
SCHEMBL28035354 0.77 NPC1 (0.42) ALDH1A1PLA2G4BCASRTP53TSHR
SCHEMBL28035370 0.77 NPC1 (0.42) ALDH1A1PLA2G4BCASRTP53TSHR
SCHEMBL28035407 0.77 NPC1 (0.42) ALDH1A1PLA2G4BCASRTP53TSHR
SCHEMBL6541581 0.77 NPC1 (0.42) ALDH1A1PLA2G4BCASRTP53TSHR
SCHEMBL6678195 0.77 NPC1 (0.42) ALDH1A1PLA2G4BCASRTP53TSHR
SCHEMBL6541323 0.77 NPC1 (0.42) ALDH1A1PLA2G4BCASRTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670184-B1 Method of demineralizing water or an aqueous solution MITSUBISHI CHEM CORP (JP) 2001-09-05 EP disclosed
US-5518627-A DEMINERALIZATION, BASIC ANION EXCHANGE RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 1996-05-21 US disclosed
EP-0670184-A2 Method of demineralizing water or an aqueous solution Mitsubishi Chemical Corporation (JP) 1995-09-06 EP disclosed