Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286561 | 0.85 | ROCK2 (0.43) | L3MBTL1CA1CA9ABCC9ABCC8 | |
| SCHEMBL17368411 | 0.77 | KIF11 (0.58) | L3MBTL1RAB9ACA1CA9NPC1 | |
| SCHEMBL7032032 | 0.75 | RAB9A (0.52) | L3MBTL1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5851814 | 0.73 | MDM2 (0.76) | L3MBTL1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4110532 | 0.73 | L3MBTL1 (0.83) | L3MBTL1RAB9AMEN1KMT2ACA1 | |
| SCHEMBL334744 | 0.71 | L3MBTL1 (0.72) | L3MBTL1RAB9ASMN1; SMN2CA1CA9 | |
| SCHEMBL18086475 | 0.71 | L3MBTL1 (0.59) | L3MBTL1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28365468 | 0.71 | CYP1A2 (0.45) | MEN1KMT2ALMNAKIF11KDM4E | |
| SCHEMBL1849484 | 0.71 | CYP1A2 (0.45) | MEN1KMT2ALMNAKIF11KDM4E | |
| SCHEMBL28365470 | 0.71 | CYP1A2 (0.45) | MEN1KMT2ALMNAKIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |