Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944581 | 0.95 | ADRB2 (0.52) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL28549048 | 0.92 | ADRB2 (0.54) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL2159817 | 0.90 | LTA4H (0.50) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL2170785 | 0.88 | FFAR1 (0.50) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL28397849 | 0.88 | LTA4H (0.49) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL7528179 | 0.88 | LMNA (0.62) | ADRB2ADRB1LMNAL3MBTL1FFAR1 | |
| SCHEMBL28543599 | 0.86 | ADRB2 (0.54) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL1744994 | 0.85 | CYP4F2 (0.59) | LMNAL3MBTL1LTA4HFFAR1PPARG | |
| SCHEMBL4513486 | 0.85 | FFAR1 (0.64) | ADRB2ADRB1LMNAL3MBTL1LTA4H | |
| SCHEMBL3985473 | 0.84 | SMN1; SMN2 (0.53) | LMNALTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4438596-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS HDAC AND DHFR DUAL-TARGETING INHIBITORS AND USE THEREOF IN PREVENTING AND TREATING MALARIA | Université de Lille (FR) | 2024-10-02 | — | — | EP | disclosed |
| EP-0882029-B1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6090836-A | DIETETICS; ADJUSTMENT OF TRIGLYCERIDE CONCENTRATION | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0882029-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | Merck & Co., Inc. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997028137-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |