SCHEMBL1744994

SCHEMBL1744994

CCOC(=O)CCc1ccc(OCCCBr)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.59
CYP4A11 Q02928 1/20 0.59
LTA4H P09960 6/20 0.54
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.49
PPARG P37231 1/20 0.48
PPARD Q03181 1/20 0.48
PPARA Q07869 1/20 0.48
CYP4Z1 Q86W10 1/20 0.48
FFAR1 O14842 1/20 0.48
CYSLTR2 Q9NS75 1/20 0.47
CYSLTR1 Q9Y271 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28538108 0.87 CYP4F2 (0.60) CYP4F2CYP4A11LTA4HLMNAL3MBTL1
SCHEMBL7279461 0.86 CYP4F2 (0.59) CYP4F2CYP4A11LTA4HLMNAL3MBTL1
SCHEMBL2444683 0.86 CYP4F2 (0.55) CYP4F2CYP4A11LTA4HLMNAL3MBTL1
SCHEMBL30257467 0.85 LTA4H (0.56) LTA4HCYSLTR2CYSLTR1MAPT
SCHEMBL7037985 0.85 ADRB2 (0.53) LTA4HLMNAL3MBTL1PPARGFFAR1
SCHEMBL3581393 0.85 TBXAS1 (0.56) LTA4HPPARG
SCHEMBL1745109 0.84 FFAR1 (0.69) CYP4F2CYP4A11LTA4HLMNAL3MBTL1
SCHEMBL8000090 0.84 LTA4H (0.57) CYP4F2CYP4A11LTA4HLMNAL3MBTL1
SCHEMBL11566476 0.83 CYP4F2 (0.56) CYP4F2CYP4A11LTA4HLMNAL3MBTL1
SCHEMBL11564286 0.83 CYP4F2 (0.56) CYP4F2CYP4A11LTA4HLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR CYP4F2 2792/4885CYP4A11 2007/4885LTA4H 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.