Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927722 | 0.81 | HPGD (0.39) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL8104229 | 0.72 | ALDH1A1 (0.42) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL29979980 | 0.71 | HTT (0.43) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL1020149 | 0.71 | HTT (0.43) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL14582034 | 0.71 | TLR8 (0.55) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL7040964 | 0.70 | HSD17B10 (0.64) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL7035923 | 0.69 | KDM4E (0.59) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL9331260 | 0.64 | MAPK1 (0.53) | LMNATSHRSMN1; SMN2HTTKDM4E | |
| SCHEMBL13451647 | 0.61 | KDM4E (0.67) | LMNATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL5390832 | 0.61 | ILK (0.44) | LMNATSHRSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6221343-B1 | Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2001-04-24 | — | — | US | disclosed |
| EP-1028120-A1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | L'OREAL (FR) | 2000-08-16 | — | — | EP | disclosed |