Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040690 | 0.78 | PIN1 (0.33) | PIN1CASP1MMP8ALDH1A1KDM4E | |
| SCHEMBL7040568 | 0.70 | CNR2 (0.33) | PIN1MMP8ALDH1A1MAPTHPGD | |
| SCHEMBL7040767 | 0.68 | CNR2 (0.39) | HSD17B10ALOX15MAPTMAPK1 | |
| SCHEMBL6055159 | 0.67 | LMNA (0.47) | LMNAALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8760976 | 0.67 | LMNA (0.47) | CASP1HSD17B10ALOX15CASP7LMNA | |
| SCHEMBL28587944 | 0.66 | PIN1 (0.42) | PIN1MMP8ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7154293 | 0.66 | TSHR (0.37) | PIN1HSD17B10MMP8ALDH1A1KDM4E | |
| SCHEMBL28565247 | 0.66 | PDE2A (0.49) | LMNACYP1A2CYP2C9CYP2C19MAPK1 | |
| SCHEMBL28608273 | 0.64 | EPHX2 (0.42) | CASP1ALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL7040571 | 0.64 | LMNA (0.39) | HSD17B10ALOX15LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925761-A | Synthesis of terfenadine and derivatives | SEPRACOR INC. (US) | 1999-07-20 | — | — | US | disclosed |