Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042436 | 0.81 | NPY1R (0.40) | NPY5RPOLBF2 | |
| SCHEMBL8126402 | 0.80 | F7 (0.39) | KDM4EGAAALDH1A1F2 | |
| SCHEMBL8587074 | 0.79 | HDAC1 (0.39) | MC4RMC5RMC3RMEN1KMT2A | |
| SCHEMBL7045274 | 0.78 | KDM4E (0.42) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7040748 | 0.78 | CA1 (0.36) | GAAMEN1KMT2APOLBF2 | |
| SCHEMBL8654742 | 0.75 | TRPM8 (0.33) | MC4R | |
| SCHEMBL7037364 | 0.75 | GAA (0.39) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8528491 | 0.74 | NPY1R (0.35) | MEN1KMT2AMAPTF2 | |
| SCHEMBL7040969 | 0.74 | NPY1R (0.42) | MC4RMC5RMC3RMC1RKDM4E | |
| SCHEMBL8526199 | 0.74 | MC4R (0.40) | MC4RMC5RMC3RMC1RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |