Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GART | P22102 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 12/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468407 | 0.90 | EPHX2 (0.38) | NPC1RAB9AGARTCTSSCYP3A4 | |
| SCHEMBL7043354 | 0.83 | EPHX2 (0.39) | NPC1RAB9AGARTCTSSCYP3A4 | |
| SCHEMBL7179327 | 0.82 | LMNA (0.38) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL7042145 | 0.82 | CTSS (0.40) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6468432 | 0.80 | GART (0.34) | NPC1RAB9AGARTCTSSCYP3A4 | |
| SCHEMBL6464414 | 0.79 | FAAH (0.38) | GARTCTSSCYP3A4CYP2C9 | |
| SCHEMBL7049143 | 0.77 | HTT (0.34) | RAB9ACTSSCYP3A4CYP2C9 | |
| SCHEMBL7183010 | 0.76 | CTSS (0.37) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6465509 | 0.75 | LMNA (0.46) | CTSSCYP3A4 | |
| SCHEMBL7049525 | 0.74 | GART (0.38) | GARTCTSSCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | NPC1 428/4885RAB9A 1895/4885GART 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.