Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043340 | 0.96 | CHRNB2 (0.39) | MEN1KMT2AHTR3APARP1 | |
| SCHEMBL7041380 | 0.88 | MEN1 (0.40) | MEN1KMT2APARP1 | |
| SCHEMBL7045272 | 0.86 | FLT3 (0.44) | MEN1KMT2AHTR3ASOS1 | |
| SCHEMBL7046813 | 0.86 | FLT3 (0.44) | MEN1KMT2ASOS1 | |
| SCHEMBL7042935 | 0.85 | HTR3A (0.42) | HTR3ASOS1 | |
| SCHEMBL7042964 | 0.85 | HTR3A (0.42) | HTR3ASOS1 | |
| SCHEMBL7457531 | 0.85 | HTR3A (0.37) | HTR3A | |
| SCHEMBL7041296 | 0.85 | HTR3A (0.40) | MEN1KMT2AHTR3ASOS1 | |
| SCHEMBL7038516 | 0.85 | KMT2A (0.43) | MEN1KMT2APARP1 | |
| SCHEMBL7039363 | 0.84 | HTR3A (0.40) | HTR3ASOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133477-B1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2004-02-18 | — | — | EP | disclosed |