SCHEMBL70441

SCHEMBL70441

CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 6/20 0.46
CYP3A4 P08684 5/20 0.46
ALOX15 P16050 1/20 0.44
SCN9A Q15858 1/20 0.44
OPRM1 P35372 2/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
DRD1 P21728 1/20 0.42
ADRA1D P25100 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HRH1 P35367 1/20 0.42
DRD3 P35462 1/20 0.42
HTR2B P41595 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5514265 0.93 CYP2D6 (0.41) CYP2D6CYP3A4ALOX15SCN9AOPRM1
SCHEMBL24238344 0.92 OPRM1 (0.42) CYP2D6CYP3A4ALOX15SCN9AOPRM1
SCHEMBL24238281 0.92 OPRM1 (0.42) CYP2D6CYP3A4ALOX15SCN9AOPRM1
SCHEMBL24238345 0.92 CYP2D6 (0.40) CYP2D6CYP3A4ALOX15SCN9AOPRM1
Maleic Acid SCHEMBL6971291 0.90 ALDH1A1 (0.49) CYP2D6CYP3A4ALOX15SCN9ATSHR
Fumaric Acid SCHEMBL6971299 0.90 ALDH1A1 (0.49) CYP2D6CYP3A4ALOX15SCN9ATSHR
SCHEMBL2265275 0.88 CYP2D6 (0.45) CYP2D6CYP3A4ALOX15SCN9AOPRM1
SCHEMBL2264060 0.88 CYP2D6 (0.45) CYP2D6CYP3A4ALOX15SCN9AOPRM1
SCHEMBL9684294 0.86 CYP2D6 (0.49) CYP2D6OPRM1CHRM2CHRM4CHRM5
SCHEMBL5745189 0.86 CYP2D6 (0.44) CYP2D6CYP3A4ALOX15SCN9AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 825 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4943641-A 3-aminoazetidine, its salts, process for their preparation and intermediates of synthesis SANOFI (FR) 1990-07-24 US claimed
EP-0155870-B1 3-AMINOAZETIDINE, ITS SALTS, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES SANOFI (FR) 1989-04-26 EP claimed
EP-0155870-A1 3-Aminoazetidine, its salts, process for their preparation and intermediates SANOFI (FR) 1985-09-25 EP claimed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
US-20260042759-A1 INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) 2026-02-12 US disclosed
US-20260021095-A1 BIFUNCTIONAL COMPOUNDS CONTAINING PYRIDO[2,3-d]PYRIMIDIN-7(8H)-ONE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS INC (US) 2026-01-22 US disclosed
US-20250367193-A1 BIFUNCTIONAL COMPOUNDS CONTAINING SUBSTITUTED PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS INC (DE) 2025-12-04 US disclosed
WO-2025235261-A1 BIFUNCTIONAL COMPOUNDS CONTAINING 2,4,5-SUBSTITUTED PYRIMIDINE DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS, INC. (US) 2025-11-13 WO disclosed
WO-2025235331-A1 BIFUNCTIONAL COMPOUNDS CONTAINING PYRAZOLOPYRIMIDINE DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS, INC. (US) 2025-11-13 WO disclosed
WO-2025235298-A1 BIFUNCTIONAL COMPOUNDS CONTAINING THIAZOLYL DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS, INC. (US) 2025-11-13 WO disclosed
US-12466823-B2 Inhibitor containing bicyclic derivative, preparation method therefor and use thereof SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2025-11-11 US disclosed
US-4594189-A Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives A. H. ROBINS COMPANY, INC. (US) 1986-06-10 US disclosed
US-4571393-A ANTICONVULSANT TREATMENT FOR MAMMALS A. H. ROBINS COMPANY, INCORPORATED (US) 1986-02-18 US disclosed
EP-0155870-A1 3-Aminoazetidine, its salts, process for their preparation and intermediates SANOFI (FR) 1985-09-25 EP disclosed
US-4505907-A ANTICONVULSANTS A. H. ROBINS COMPANY, INC. (US) 1985-03-19 US disclosed
EP-0131435-A1 Process for preparing 3-phenoxy-1-azetidines and carboxamide derivatives A.H. ROBINS COMPANY, INCORPORATED (US) 1985-01-16 EP disclosed
EP-0102740-A1 N-formyl and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides and their preparation and use A.H. ROBINS COMPANY, INCORPORATED (US) 1984-03-14 EP disclosed
EP-0102194-A1 3-Phenoxy-1-azetidinecarboxamides and their use and preparation A.H. ROBINS COMPANY, INCORPORATED (US) 1984-03-07 EP disclosed
US-4379151-A 3-Phenoxyazetidines for anorexigenic activity A. H. ROBINS COMPANY, INC. (US) 1983-04-05 US disclosed
US-4183923-A 3-ALKANESULFONYLOXYAZETIDINES SCHERING CORPORATION (US) 1980-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021095-A1 BIFUNCTIONAL COMPOUNDS CONTAINING PYRIDO[2,3-d]PYRIMIDIN-7(8H)-ONE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY PSMB2, PSMB7, MDM2 CYP2D6 2264/4885CYP3A4 2789/4885ALOX15 3772/4885
US-20260042759-A1 INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF FAR1, CYP4A11, CYP11B1 CYP2D6 724/4885CYP3A4 392/4885ALOX15 416/4885
US-20250367193-A1 BIFUNCTIONAL COMPOUNDS CONTAINING SUBSTITUTED PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY CDK2, SKP2, CCNK CYP2D6 3160/4885CYP3A4 3662/4885ALOX15 4281/4885
US-12466823-B2 Inhibitor containing bicyclic derivative, preparation method therefor and use thereof RET, REL, GOT1 CYP2D6 746/4885CYP3A4 101/4885ALOX15 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.