Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063609 | 0.87 | DRD2 (0.40) | CA1CA2KIF11PDE4APDE4B | |
| SCHEMBL3495660 | 0.82 | DRD2 (0.43) | CA1CA2PDE4APDE4BPDE4C | |
| SCHEMBL7045469 | 0.82 | DRD2 (0.43) | CA1CA2PDE4APDE4BPDE4C | |
| SCHEMBL5889322 | 0.77 | GRIN2B (0.49) | KIF11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4148437 | 0.77 | GRIN2B (0.49) | KIF11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7041726 | 0.76 | CA2 (0.41) | CA1CA2PDE4APDE4BPDE4C | |
| SCHEMBL13945021 | 0.74 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DACHE | |
| SCHEMBL14474703 | 0.74 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DACHE | |
| SCHEMBL575913 | 0.73 | CA2 (0.51) | CA1CA2KIF11JAK2JAK3 | |
| SCHEMBL5620504 | 0.73 | GRIN2B (0.46) | PDE4APDE4BPDE4CPDE4DSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220386-A1 | Delta 1-pyrrolines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220386-A1 | Delta 1-pyrrolines for use as pesticides | DDT, OPRD1, PRMT1 | CA1 2269/4885CA2 2815/4885AKR1C3 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.