Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468767 | 1.00 | CTSS (0.36) | CTSSKDM4ECYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL7045927 | 0.91 | CTSS (0.38) | CTSSKDM4ECYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL6467525 | 0.89 | CTSS (0.35) | CTSSKDM4ECYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL6467381 | 0.87 | CTSS (0.36) | CTSSKDM4ECYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL6467383 | 0.85 | FAAH (0.40) | CTSSKDM4EALDH1A1 | |
| SCHEMBL7048621 | 0.83 | CTSS (0.35) | CTSSCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL7042156 | 0.82 | CTSS (0.36) | CTSSKDM4EALDH1A1 | |
| SCHEMBL7187232 | 0.81 | CTSS (0.38) | CTSSKDM4ECYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL7114802 | 0.80 | LMNA (0.38) | CTSSKDM4EALDH1A1 | |
| SCHEMBL6464598 | 0.79 | CTSS (0.35) | CTSSKDM4ECYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | CTSS 9/4885KDM4E 2918/4885CYP3A4 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.