Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677281 | 0.85 | LTA4H (0.45) | CYP3A4TSHRFFAR1SLC6A4SLC6A2 | |
| SCHEMBL7049085 | 0.82 | LTA4H (0.35) | ALDH1A1HTTMAPK1L3MBTL1LMNA | |
| SCHEMBL6933864 | 0.80 | THRA (0.32) | LMNACYP2C9CYP3A4TSHRPOLB | |
| SCHEMBL7239465 | 0.79 | NCOA1 (0.42) | ALDH1A1HTTMAPK1L3MBTL1LMNA | |
| SCHEMBL29812870 | 0.78 | CYP3A4 (0.40) | ALDH1A1HTTMAPK1L3MBTL1LMNA | |
| SCHEMBL1071989 | 0.78 | CYP3A4 (0.40) | ALDH1A1HTTMAPK1L3MBTL1LMNA | |
| SCHEMBL8776759 | 0.76 | RIPK1 (0.53) | ALDH1A1HTTMAPK1L3MBTL1LMNA | |
| SCHEMBL1949466 | 0.76 | TSHR (0.41) | ALDH1A1HTTMAPK1LMNACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL9248440 | 0.75 | RIPK1 (0.52) | ALDH1A1HTTMAPK1L3MBTL1LMNA | |
| SCHEMBL242048 | 0.75 | LTA4H (0.50) | CYP3A4TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810244-B1 | Aromatic polycarbodiimide and sheet using it | NITTO DENKO CORP (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-5859170-A | CONTAINING SILOXANE BOND IN POLYMER MAIN CHAIN; HEAT RESISTANCE, STORAGE STABILITY | NITTO DENKO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0810244-A2 | Aromatic polycarbodiimide and sheet using it | NITTO DENKO CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |