Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677281 | 0.88 | LTA4H (0.45) | LTA4HPTGS2CYP3A4TSHRLPAR1 | |
| SCHEMBL7046465 | 0.82 | ALDH1A1 (0.37) | LTA4HPTGS2CYP3A4TSHRFFAR1 | |
| SCHEMBL3382230 | 0.79 | CYP3A4 (0.40) | CYP3A4TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL7239465 | 0.77 | NCOA1 (0.42) | PTGS2CYP3A4TSHRLMNAALDH1A1 | |
| SCHEMBL1071989 | 0.75 | CYP3A4 (0.40) | CYP3A4TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL721404 | 0.75 | NCOA1 (0.49) | LTA4HPTGS2CYP3A4TSHRAR | |
| SCHEMBL29812870 | 0.75 | CYP3A4 (0.40) | CYP3A4TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL242048 | 0.72 | LTA4H (0.50) | LTA4HCYP3A4TSHRPARP10 | |
| SCHEMBL7181943 | 0.72 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL50333 | 0.72 | CYP3A4 (0.54) | LTA4HCYP3A4TSHRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10251511-A | — | — | None | — | — | JP | disclosed |
| EP-0810244-B1 | Aromatic polycarbodiimide and sheet using it | NITTO DENKO CORP (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-5859170-A | CONTAINING SILOXANE BOND IN POLYMER MAIN CHAIN; HEAT RESISTANCE, STORAGE STABILITY | NITTO DENKO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| JP-H10251511-A | PASTE COMPOSITION | NITTO DENKO CORP | 1998-09-22 | — | — | JP | disclosed |
| EP-0810244-A2 | Aromatic polycarbodiimide and sheet using it | NITTO DENKO CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |