Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042640 | 0.91 | SMN1; SMN2 (0.46) | POLBMAPTTDP1RAB9ASMN1; SMN2 | |
| SCHEMBL6552425 | 0.82 | LTB4R (0.57) | LTB4RHSD17B10ALDH1A1KMT2AGAA | |
| SCHEMBL6551978 | 0.77 | HTT (0.49) | LTB4RPOLBLMNA | |
| SCHEMBL7046180 | 0.77 | EPHX2 (0.50) | RAB9ASMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL7044700 | 0.77 | SMN1; SMN2 (0.52) | POLBHSD17B10RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6553452 | 0.75 | TDP1 (0.50) | LTB4RPOLBMAPTTDP1RAB9A | |
| SCHEMBL7046185 | 0.75 | CDK5 (0.49) | LTB4RRAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22048694 | 0.72 | LTB4R (0.50) | LTB4RPOLBMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL7044623 | 0.72 | NPC1 (0.43) | LTB4RPOLBRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4437426 | 0.70 | MMP2 (0.58) | POLBMAPTTDP1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |