Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.82 |
| ▸ | RAB9A | P51151 | 4/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | RORC | P51449 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129857 | 0.84 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7129854 | 0.82 | RORC (0.59) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7124311 | 0.80 | SORT1 (0.75) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7119948 | 0.80 | SMN1; SMN2 (0.83) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7118616 | 0.79 | SMN1; SMN2 (0.67) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7120764 | 0.77 | KMT2A (0.76) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL18147432 | 0.77 | RORC (0.80) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL2585157 | 0.77 | TP53 (0.82) | NPC1RAB9AKMT2AMEN1PKM | |
| SCHEMBL18147747 | 0.77 | SMN1; SMN2 (0.64) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL7130662 | 0.76 | RORC (0.73) | NPC1RAB9AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130343-A1 | Fat accumulation-modulating compounds | ADIPOGENIX, INC. (US) | 2003-07-10 | — | — | US | claimed |
| WO-2003013516-A1 | FAT ACCUMULATION-MODULATING COMPOUNDS | ADIPOGENIX, INC. (US) | 2003-02-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130343-A1 | Fat accumulation-modulating compounds | FABP4, LIPC, PLIN1 | NPC1 92/4885RAB9A 2609/4885KMT2A 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.