Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022399 | 0.85 | GRIN2D (0.49) | HSD17B1HSD17B2GABRA1GABRB2GRIN2D | |
| SCHEMBL21119018 | 0.81 | GABRA1 (0.47) | HSD17B1HSD17B2GABRA1GABRB2GRIN2D | |
| SCHEMBL5083275 | 0.81 | HSD17B1 (0.56) | HSD17B1HSD17B2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL2608798 | 0.79 | HSD17B1 (0.59) | HSD17B1HSD17B2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL27217470 | 0.79 | LMNA (0.38) | GABRA1GABRB2CYP1A2CYP3A4MAPT | |
| SCHEMBL2964707 | 0.79 | CYP1A2 (0.48) | HSD17B1HSD17B2GABRA1GABRB2CYP1A2 | |
| SCHEMBL19425721 | 0.75 | HSD17B1 (0.55) | HSD17B1HSD17B2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL10054046 | 0.75 | HSD17B1 (0.59) | HSD17B1HSD17B2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL11509499 | 0.74 | CYP2A6 (0.46) | GABRA1GABRB2CYP1A2CYP3A4LMNA | |
| SCHEMBL19615843 | 0.74 | HSD17B1 (0.50) | HSD17B1HSD17B2GRIN2DGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165322-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20030028055-A1 | High quality bisphenol a and preparation process thereof | MITSUI CHEMICALS, INC. (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1149816-A1 | HIGH-QUALITY BISPHENOL A AND PROCESS FOR PRODUCING THE SAME | Mitsui Chemicals, Inc. (JP) | 2001-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028055-A1 | High quality bisphenol a and preparation process thereof | TET2, PCBP1, PAH | HSD17B1 1965/4885HSD17B2 1480/4885GABRA1 3840/4885 |
| US-20120165322-A1 | RHO KINASE INHIBITORS | ROCK1, ROCK2, RHOA | HSD17B1 1547/4885HSD17B2 1666/4885GABRA1 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.