Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053974 | 0.73 | MEP1A (0.39) | MAPTALDH1A1GLAGRIA2GRIN1 | |
| SCHEMBL2660512 | 0.72 | GLA (0.58) | MAPTALDH1A1GLASCN8A | |
| SCHEMBL7053242 | 0.71 | SLC6A2 (0.36) | VNN1MAPTALDH1A1GLA | |
| SCHEMBL6960353 | 0.69 | ALDH1A1 (0.41) | VNN1MAPTALDH1A1GLAPDE2A | |
| SCHEMBL411143 | 0.68 | GLA (0.54) | VNN1GLASCN8A | |
| SCHEMBL320058 | 0.67 | LOXL2 (0.59) | VNN1MAPTGLACYP3A4KDM4E | |
| SCHEMBL30471916 | 0.67 | LOXL2 (0.59) | VNN1MAPTGLACYP3A4KDM4E | |
| SCHEMBL7053828 | 0.67 | NTRK1 (0.45) | VNN1MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6955432 | 0.67 | MAPT (0.46) | VNN1MAPTALDH1A1GLAPDE2A | |
| SCHEMBL21316490 | 0.66 | GLA (0.55) | MAPTALDH1A1GLASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |