Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053242 | 0.85 | SLC6A2 (0.36) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7052131 | 0.83 | CNR1 (0.38) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7053432 | 0.81 | MEP1A (0.37) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7056941 | 0.79 | MEP1A (0.37) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14019167 | 0.75 | MEP1A (0.40) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7050677 | 0.73 | VNN1 (0.41) | GLAALDH1A1MAPTGRIA2GRIN1 | |
| SCHEMBL7052650 | 0.71 | MGLL (0.37) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19049392 | 0.67 | SLC6A2 (0.53) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2660512 | 0.67 | GLA (0.58) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6964408 | 0.65 | ALDH1A1 (0.43) | MEP1AMEP1BSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |