SCHEMBL7050877

SCHEMBL7050877

CCCCC(C)(Oc1ccc(Oc2ccc(C(Cl)(Cl)Cl)cn2)cc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
GFER P55789 1/20 0.43
MAPT P10636 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LIPE Q05469 6/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
GRN P28799 2/20 0.38
SORT1 Q99523 2/20 0.38
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
CYP3A4 P08684 1/20 0.37
GAA P10253 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988337 0.89 LMNA (0.58) LMNAMAPTLIPERAB9ACYP3A4
SCHEMBL5174065 0.89 LMNA (0.58) LMNAMAPTLIPERAB9ACYP3A4
SCHEMBL7050883 0.76 CTRC (0.45) LMNAGFERMAPTALDH1A1LIPE
SCHEMBL11165307 0.76 PPARA (0.46) RAB9APOLBPPARGPPARACYP2C9
Diallate SCHEMBL9819269 0.75 LIPE (0.41) LMNALIPERAB9APLAAT3PLAAT5
SCHEMBL7050879 0.75 L3MBTL1 (0.45) LMNAALDH1A1GAA
SCHEMBL10495365 0.75 P2RX3 (0.43) LMNAALDH1A1RAB9APPARGPPARA
SCHEMBL10853659 0.74 LIPE (0.55) LMNAMAPTLIPERAB9ACYP3A4
SCHEMBL4550641 0.73 PPARA (0.54) PPARGPPARAPSEN1PSEN2APH1B
SCHEMBL11002855 0.73 LMNA (0.52) LMNAMAPTLIPERAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788740-B1 Composite particle aqueous suspension and process for producing same HODOGAYA CHEMICAL CO LTD (JP) 2003-04-16 EP disclosed
EP-0788740-A1 Composite particle aqueous suspension and process for producing same HODOGAYA CHEMICAL CO LTD (JP) 1997-08-13 EP disclosed