SCHEMBL7050883

SCHEMBL7050883

CCCCCC(Oc1ccc(Oc2ccc(C(Cl)(Cl)Cl)cn2)cc1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.45
PPARG P37231 6/20 0.41
PPARA Q07869 6/20 0.41
PTGES O14684 1/20 0.40
ALOX5 P09917 1/20 0.40
LMNA P02545 1/20 0.40
GFER P55789 1/20 0.39
LIPE Q05469 4/20 0.38
RAB9A P51151 1/20 0.38
ACACB O00763 1/20 0.38
ALDH2 P05091 1/20 0.38
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
GRN P28799 1/20 0.37
SORT1 Q99523 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174070 0.89 LMNA (0.53) CTRCPPARGPPARALMNALIPE
SCHEMBL7191647 0.89 LMNA (0.53) CTRCPPARGPPARALMNALIPE
SCHEMBL988340 0.89 LMNA (0.53) CTRCPPARGPPARALMNALIPE
SCHEMBL11022294 0.81 LMNA (0.56) PPARGPPARALMNALIPERAB9A
SCHEMBL7050879 0.80 L3MBTL1 (0.45) LMNAACACBALDH1A1
SCHEMBL7050877 0.76 LMNA (0.44) PPARGPPARALMNAGFERLIPE
SCHEMBL31144647 0.76 CTRC (0.63) CTRCPPARGPPARAPTGESALOX5
SCHEMBL10495363 0.76 CTRC (0.45) CTRCPPARGPPARAPTGESALOX5
SCHEMBL10853665 0.74 LIPE (0.52) PPARGPPARALMNALIPERAB9A
SCHEMBL6545280 0.72 PPARA (0.68) CTRCPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788740-B1 Composite particle aqueous suspension and process for producing same HODOGAYA CHEMICAL CO LTD (JP) 2003-04-16 EP disclosed