SCHEMBL70512

SCHEMBL70512

c1ccc2c(c1)Cc1nnccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.47
MAOA P21397 2/20 0.39
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
CYP19A1 P11511 2/20 0.37
TNF P01375 2/20 0.37
BCHE P06276 1/20 0.36
CES1 P23141 1/20 0.36
CYP17A1 P05093 1/20 0.36
PLK4 O00444 1/20 0.35
DAPK3 O43293 1/20 0.35
PIM1 P11309 1/20 0.35
PDGFRA P16234 1/20 0.35
LTK P29376 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6269850 0.82 CYP11B2 (0.43) CYP19A1CES1CYP11B2MIFPKM
SCHEMBL13262088 0.79 CYP11B2 (0.45) MAOAMAPTHPGDCYP19A1BCHE
SCHEMBL17264310 0.78 SIGMAR1 (0.41) MAOAMAOB
SCHEMBL17264313 0.76 TDP1 (0.33) METAP2KDM4EMAPTSMN1; SMN2LMNA
SCHEMBL8035058 0.75 KDM4E (0.32) METAP2KDM4ENPC1MAPTRAB9A
SCHEMBL30011414 0.75 METAP2 (0.46) METAP2MAOAKDM4ENPC1MAPT
SCHEMBL51294 0.75 METAP2 (0.46) METAP2MAOAKDM4ENPC1MAPT
SCHEMBL29360004 0.75 METAP2 (0.46) METAP2MAOAKDM4ENPC1MAPT
SCHEMBL27174135 0.75 METAP2 (0.46) METAP2MAOAKDM4ENPC1MAPT
SCHEMBL2485732 0.74 METAP2 (0.42) METAP2MAOAKDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111987230-B Organic light emitting device and apparatus including the same 三星显示有限公司 2025-02-28 CN claimed
CN-115850256-B Diazafluorene compound, material for organic electroluminescent device and organic electroluminescent device 东莞伏安光电科技有限公司 2025-02-07 CN claimed
CN-118561836-A Heterocyclic derivative and organic electroluminescent device comprising the same 海宁奕诺炜特科技有限公司 2024-08-30 CN claimed
CN-118440075-A Organic electroluminescent compound and organic electroluminescent element comprising same 海宁奕诺炜特科技有限公司 2024-08-06 CN claimed
WO-2024108789-A1 DIAZAFLUORENE COMPOUND, MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE, AND ORGANIC LIGHT-EMITTING DEVICE 东莞伏安光电科技有限公司 2024-05-30 WO claimed
US-20230231508-A1 WINDOWS WITH POWER GENERATION FROM TRANSPARENT SOLAR ENERGY HARVESTING DEVICES COMPRISING WAVELENGTH-SPECIFIC ABSORBERS ANDLUCA TECHNOLOGIES INC. 2023-07-20 US claimed
CN-113150243-B Dynamic self-healing antirust epoxy resin and preparation method thereof 中国船舶重工集团公司第七二五研究所 2023-06-23 CN claimed
CN-115850256-A Diazafluorene compound, material for organic electroluminescent device and organic electroluminescent device 东莞伏安光电科技有限公司 2023-03-28 CN claimed
US-20220340571-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-10-27 US claimed
US-11462703-B2 Organic light-emitting device and apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-10-04 US claimed
EP-1868600-A1 SPIROCYCLIC CYCLOHEXANE DERIVATIVES FOR USE IN THE TREATMENT OF SUBSTANCE DEPENDENCY Grünenthal GmbH (DE) 2007-12-26 EP claimed
WO-2006108565-A1 SPIROCYCLIC CYCLOHEXANE DERIVATIVES FOR USE IN THE TREATMENT OF SUBSTANCE DEPENDENCY Grünenthal GmbH (DE) 2006-10-19 WO claimed
US-20040028612-A1 Optical determination of glucose utilizing boronic acid adducts REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2004-02-12 US claimed
US-6653141-B2 In vitro detection of polyhydroxyl-substituted organic molecules; obtain sample, incubate in fluorescent dye exposure to excitation light detect and measure signal THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-11-25 US claimed
US-6627177-B2 Obtaining flurorophore dye which is compatible with the analyte solution; combining withboronic acid-containing quencher molecule; contacting with excitation light source coupled with a detector; producing signal; quantification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-09-30 US claimed
EP-1340076-A2 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS The Regents of the University of California (US) 2003-09-03 EP claimed
WO-2002046752-A9 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS UNIV CALIFORNIA (US) 2002-08-29 WO claimed
US-20020106326-A1 Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof CALIFORNIA, UNIVERSITY OF THE REGENTS OF THE 2002-08-08 US claimed
US-20020106810-A1 Polyhydroxyl-substituted organic molecule sensing optical in vitro method utilizing a boronic acid adduct and the device thereof REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2002-08-08 US claimed
WO-2002046752-A2 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-06-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220340571-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME CLIC1, CLCN2, CYBA METAP2 3188/4885MAOA 3216/4885KDM4E 3608/4885
US-20040028612-A1 Optical determination of glucose utilizing boronic acid adducts NISCH, BLVRB, FOSB METAP2 4442/4885MAOA 1128/4885KDM4E 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.