Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.80 |
| ▸ | MMP9 | P14780 | 10/20 | 0.80 |
| ▸ | MMP3 | P08254 | 8/20 | 0.80 |
| ▸ | MMP13 | P45452 | 7/20 | 0.80 |
| ▸ | MMP1 | P03956 | 5/20 | 0.80 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.52 |
| ▸ | MMP14 | P50281 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039450 | 0.89 | MMP9 (0.77) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7054085 | 0.89 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7053227 | 0.87 | MMP3 (0.81) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7053947 | 0.84 | MMP3 (0.59) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8041322 | 0.81 | MMP3 (0.84) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8029542 | 0.77 | MMP3 (0.79) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7051704 | 0.77 | MMP3 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7055853 | 0.76 | MMP3 (0.74) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL5191414 | 0.75 | MMP2 (0.47) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8039454 | 0.74 | MMP3 (0.57) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979816-B1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-05-02 | — | — | EP | disclosed |
| EP-0979816-A1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-02-16 | — | — | EP | disclosed |