Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053432 | 0.90 | MEP1A (0.37) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL7053974 | 0.79 | MEP1A (0.39) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL7052131 | 0.78 | CNR1 (0.38) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL7053242 | 0.76 | SLC6A2 (0.36) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL14019167 | 0.70 | MEP1A (0.40) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL7052650 | 0.70 | MGLL (0.37) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL6957643 | 0.67 | MEP1A (0.42) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL6964459 | 0.66 | IDH1 (0.37) | MEP1AMEP1BCHRM2CHRM1CHRM3 | |
| SCHEMBL7050677 | 0.65 | VNN1 (0.41) | GRIA2GRIN1GRIN2AGLSVNN1 | |
| SCHEMBL6971432 | 0.64 | MEP1A (0.40) | MEP1AMEP1BCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |