Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | HTR3A | P46098 | 4/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610425 | 0.89 | SLC6A2 (0.50) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| SCHEMBL7255537 | 0.83 | HTR3E (0.68) | HTR6HTR1AHTR3AHTR3EHTR3B | |
| SCHEMBL6927912 | 0.82 | HTR1A (0.64) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| Hydrochloric Acid SCHEMBL7302055 | 0.81 | LMNA (0.65) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| SCHEMBL2873088 | 0.81 | HTR3E (0.68) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| SCHEMBL6777684 | 0.81 | ADRA1D (0.48) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| SCHEMBL5269642 | 0.80 | DRD2 (0.54) | HTR1ASLC6A4DRD2CYP2C19DRD3 | |
| Hydrochloric Acid SCHEMBL27465755 | 0.80 | LMNA (0.67) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| SCHEMBL6194097 | 0.77 | SLC6A2 (0.52) | HTR6HTR1ASLC6A2SLC6A4HTR3A | |
| SCHEMBL5414291 | 0.77 | HTR1A (0.49) | HTR6HTR1ASLC6A2SLC6A4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181446-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-09-25 | — | — | US | disclosed |
| US-20030162777-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162777-A1 | Novel N-acylated heterocycles | HTR1A, HTR1D, HTR1E | HTR6 38/4885HTR1A 1/4885SLC6A2 182/4885 |
| US-20030181446-A1 | Novel N-acylated heterocycles | HTR1A, HTR1E, HTR2C | HTR6 20/4885HTR1A 1/4885SLC6A2 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.