SCHEMBL7636718

SCHEMBL7636718

C[Si](C)(Cl)c1ccc(S)cc1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.41
TRPV4 Q9HBA0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705667 0.85 ALDH1A1 (0.36)
SCHEMBL801429 0.77
SCHEMBL30965311 0.77 ESR1 (0.44)
SCHEMBL10318540 0.77 NR1H2 (0.41)
SCHEMBL1328546 0.77 NR1H2 (0.41) IDO1TRPV4
SCHEMBL80628 0.74 ACHE (0.47)
SCHEMBL7913246 0.74 LMNA (0.47) IDO1
SCHEMBL10317698 0.72 CYP2A6 (0.44) IDO1
SCHEMBL1599765 0.72 ACHE (0.41) IDO1
SCHEMBL68909 0.71 ESR1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0791634-B1 Fire retardant polyester resin composition and process for producing the same MITSUBISHI ENG PLASTICS CORP (JP) 2002-11-06 EP disclosed
US-5770644-A FIREPROOFING MOLDING MATERIAL BLENDS COMPRISING A POLYESTERS, A POLYPHENYLENE ETHER RESIN AND/OR POLYPHENYLENE SULFIDE RESIN AND A COMPATIBILIZING AGENT; NONHYDROLYSIS, FLEXIBILITY, DIMENSION STABILITY, CORROSION RESISTANCE MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) 1998-06-23 US disclosed