SCHEMBL705708

SCHEMBL705708

CCOC(=O)Cc1cccc(Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 2/20 0.51
PKM P14618 1/20 0.48
LMNA P02545 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
TTR P02766 1/20 0.46
CYP2C9 P11712 1/20 0.46
TBXA2R P21731 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
PNMT P11086 1/20 0.46
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
MAPT P10636 1/20 0.45
IDO1 P14902 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29965785 1.00 NLRP3 (0.51) NLRP3PKMLMNAALDH1A1HTT
SCHEMBL6367097 0.88 NLRP3 (0.48) NLRP3PKMLMNAALDH1A1HTT
SCHEMBL513530 0.88 PKM (0.53) NLRP3PKMLMNAALDH1A1KDM4E
SCHEMBL2412305 0.87 LMNA (0.44) NLRP3LMNAALDH1A1KDM4EUSP2
SCHEMBL18169344 0.87 NLRP3 (0.49) NLRP3PKMLMNAALDH1A1HTT
SCHEMBL1625354 0.85 NLRP3 (0.48) NLRP3PKMLMNAALDH1A1HTT
SCHEMBL1626000 0.85 NLRP3 (0.48) NLRP3PKMLMNAALDH1A1HTT
SCHEMBL17061213 0.84 ALDH1A1 (0.46) NLRP3PKMLMNAALDH1A1SMN1; SMN2
SCHEMBL31075841 0.84 NLRP3 (0.47) NLRP3PKMLMNAALDH1A1HTT
SCHEMBL2422452 0.84 TDP1 (0.47) LMNAALDH1A1HTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391779-B2 Ethylene propylene diene monomer (EPDM) and nonconjugated diene copolymers and methods for making same Lion Copolymers Holdings, LLC (US) 2025-08-19 US claimed
US-20240336715-A1 ETHYLENE PROPYLENE DIENE MONOMER (EPDM) AND NONCONJUGATED DIENE COPOLYMERS AND METHODS FOR MAKING SAME LION COPOLYMER GEISMAR, LLC (US) 2024-10-10 US claimed
US-12049554-B2 Ethylene propylene diene monomer (EPDM) and vinyl norbornene diene (VNB) copolymers and methods of making same LION COPOLYMERS GEISMAR, LLC (US) 2024-07-30 US claimed
US-20230138702-A1 ETHYLENE PROPYLENE DIENE MONOMER (EPDM) AND VINYL NORBORNENE DIENE (VNB) COPOLYMERS AND METHODS OF MAKING SAME LION COPOLYMER GEISMAR, LLC (US) 2023-05-04 US claimed
CN-111499788-B Ethylene-propylene-non-conjugated diene copolymer and synthesis method thereof 中国石油天然气股份有限公司 2022-11-04 CN claimed
CN-111499788-A Ethylene-propylene-non-conjugated diene copolymer and synthesis method thereof 中国石油天然气股份有限公司 2020-08-07 CN claimed
EP-2782940-B1 PROCESS FOR THE PREPARATION OF A COPOLYMER OF ETHYLENE VERSALIS SPA (IT) 2018-03-21 EP claimed
US-9701764-B2 Process for the preparation of a copolymer of ethylene VERSALIS S.P.A. (IT) 2017-07-11 US claimed
US-9574034-B1 Process for making high molecular weight tetrapolymer and articles produced therefrom LION COPOLYMER GEISMAR, LLC (US) 2017-02-21 US claimed
US-9574033-B1 Process for continuously making high molecular weight tetrapolymer for use in anti-vibration applications LION COPOLYMER GEISMAR, LLC (US) 2017-02-21 US claimed
WO-2013076699-A1 PROCESS FOR THE PREPARATION OF A COPOLYMER OF ETHYLENE VERSALIS S.P.A. (IT) 2013-05-30 WO claimed
CN-101092466-A Vanadium catalytic system for copolymerization of ethylene, propylene and diene and application thereof PETROCHINA CO LTD (CN) 2007-12-26 CN claimed
US-20050282982-A1 Amido complexes of vanadium for olefin polymerization LANXESS DEUTSCHLAND GMBH (DE) 2005-12-22 US claimed
CN-1709920-A Amido complexes of vanadium for olefin polymerization LANXESS DEUTSCHLAND GMBH (DE) 2005-12-21 CN claimed
EP-1113028-B1 Process for production of olefin polymer with long chain branching BAYER AG (US) 2004-03-31 EP claimed
US-6384162-B1 COORDINATION CATALYST OF VANADIUM TRIS DIKETATE, HALOGENATED ORGANOALUMINUM, AND CHLORINATED ESTER ACTIVATOR; ETHYLENE PROPYLENE TETRAPOLYMERS WITH TWO DIOLEFIN MONOMERS SUCH AS 5-ETHYLIDENE-2-NORBORNENE AND 5-VINYLIDINE-2-NORBORNENE BAYER AKTIENGESELLSCHAFT (DE) 2002-05-07 US claimed
EP-0950670-B1 Olefin polymerization process and catalyst system therefor BAYER INC (CA) 2002-03-27 EP claimed
EP-1113028-A1 Process for production of olefin polymer with long chain branching Bayer Inc. (CA) 2001-07-04 EP claimed
EP-0967231-A1 Process for the production of olefin polymer with long chain branching Bayer Inc. (CA) 1999-12-29 EP claimed
EP-0950670-A2 Olefin polymerization process and catalyst system therefor Bayer Inc. (CA) 1999-10-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282982-A1 Amido complexes of vanadium for olefin polymerization NOX4, NOXO1, COG4 NLRP3 3394/4885PKM 3222/4885LMNA 4618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.