Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056890 | 0.76 | HPGD (0.41) | SLC6A3TDP1HPGDGAACYP3A4 | |
| SCHEMBL8041595 | 0.75 | RAB9A (0.36) | — | |
| SCHEMBL2240777 | 0.73 | SLC18A3 (0.39) | — | |
| SCHEMBL7058258 | 0.72 | ALDH1A1 (0.31) | SLC6A3HPGDALDH1A1 | |
| SCHEMBL16684620 | 0.72 | SLC6A3 (0.34) | SLC6A3HPGDALDH1A1 | |
| SCHEMBL28774732 | 0.71 | SLC6A3 (0.33) | SLC6A3HPGDALDH1A1 | |
| SCHEMBL5983900 | 0.69 | SIGMAR1 (0.44) | CYP2D6CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7771376 | 0.69 | HPGD (0.42) | SLC6A3TDP1HPGDGAACYP3A4 | |
| SCHEMBL5455484 | 0.68 | SLC6A3 (0.41) | SLC6A3TDP1HPGDGAACYP2D6 | |
| SCHEMBL51579 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863185-B1 | Flame retardant additive based on polysiloxane for aromatic polymers | GEN ELECTRIC (US) | 2003-05-14 | — | — | EP | claimed |