Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041595 | 0.91 | RAB9A (0.36) | SLC18A3MGLL | |
| SCHEMBL7249559 | 0.85 | MEN1 (0.40) | SLC18A3MEN1KMT2AMGLL | |
| SCHEMBL16684620 | 0.82 | SLC6A3 (0.34) | SLC18A3MGLL | |
| SCHEMBL28774732 | 0.81 | SLC6A3 (0.33) | SLC18A3MGLL | |
| SCHEMBL6543644 | 0.79 | KIF11 (0.35) | MEN1KMT2ALMNA | |
| SCHEMBL6432221 | 0.76 | MGLL (0.34) | MEN1KMT2AMGLL | |
| SCHEMBL7058258 | 0.76 | ALDH1A1 (0.31) | LMNA | |
| SCHEMBL5983900 | 0.76 | SIGMAR1 (0.44) | MEN1KMT2A | |
| SCHEMBL4929388 | 0.75 | CYP1A2 (0.36) | — | |
| SCHEMBL516195 | 0.73 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190467-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2011-08-04 | — | — | US | disclosed |
| US-20090276042-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
| WO-2008051947-A2 | HIGHLY FILLED POLYMER MATERIALS | LORD CORPORATION (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-0665007-B1 | Method of making clear antiperspirant gels | DOW CORNING (US) | 1999-03-10 | — | — | EP | disclosed |
| US-5492691-A | COMBINING ANTIPERSPIRANT, A CLEAR ANHYDROUS ORGANIC OIL-FREE GEL FORMED WITH 12-HYDROXYSTEARIC ACID GELATOR AND AN AROMATIC CONTAINING SILICONE FLUID OR BLEND OF SILICONE FLUIDS | DOW CORNING CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0665256-A2 | Pristine phenylpropylalkylsiloxanes | DOW CORNING CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0665007-A1 | Method of making clear antiperspirant gels | DOW CORNING CORPORATION (US) | 1995-08-02 | — | — | EP | disclosed |
| US-5384383-A | Pristine phenylpropylalkylsiloxanes | DOW CORNING CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | PBK, B2M, CD79B | SLC18A3 4501/4885MEN1 782/4885KMT2A 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.