Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240777 | 0.91 | SLC18A3 (0.39) | MGLLSLC18A3 | |
| SCHEMBL16684620 | 0.84 | SLC6A3 (0.34) | RAB9ASMN1; SMN2MGLLSLC18A3 | |
| SCHEMBL28774732 | 0.83 | SLC6A3 (0.33) | RAB9ASMN1; SMN2MGLLSLC18A3 | |
| SCHEMBL7249559 | 0.79 | MEN1 (0.40) | MGLLSLC18A3 | |
| SCHEMBL6432221 | 0.78 | MGLL (0.34) | RAB9ASMN1; SMN2MGLL | |
| SCHEMBL7058258 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL8602242 | 0.76 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2MGLL | |
| SCHEMBL7057499 | 0.75 | SLC6A3 (0.36) | — | |
| SCHEMBL21670829 | 0.75 | CYP1A2 (0.35) | MGLL | |
| SCHEMBL4355747 | 0.74 | EPHX2 (0.36) | RAB9ASMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757082-B1 | Storage stable dispersions of finely divided solids in organosiloxane compositions | DOW CORNING (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0710704-B1 | Curable silicone rubber composition | DOW CORNING (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0757082-A2 | Storage stable dispersions of finely divided solids in organosiloxane compositions | DOW CORNING CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5563197-A | HOMOGENEITY THIXOTROPIC LIQUID, PASTE OR GEL; BLENDING | DOW CORNING CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0731142-A2 | Thixotropic organosiloxane compositions | DOW CORNING CORPORATION (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0710704-A2 | Curable silicone rubber composition | DOW CORNING CORPORATION (US) | 1996-05-08 | — | — | EP | disclosed |
| US-4022747-A | DIORGANO-POLY-SILOXANE, ORGANO-POLY-SILOXANE, SILICA FILLER, ORGANIC PEROXIDE | SHIN-ETSU CHEMICAL COMPANY LIMITED (JA) | 1977-05-10 | — | — | US | disclosed |