Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.35 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764584 | 0.84 | FAAH (0.35) | TGM2FAAHBCHE | |
| SCHEMBL5764582 | 0.77 | JAK2 (0.41) | KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL5768278 | 0.77 | JAK2 (0.41) | KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL5764872 | 0.77 | JAK2 (0.41) | KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL4615941 | 0.76 | OPRK1 (0.51) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2706511 | 0.75 | OPRD1 (0.40) | KDM1ANPC1RAB9ASMN1; SMN2CTSV | |
| SCHEMBL23527973 | 0.74 | DPP4 (0.40) | KMT2AKDM1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23528036 | 0.74 | CTSL (0.42) | NPC1RAB9ASMN1; SMN2CTSVCTSL | |
| SCHEMBL4602481 | 0.73 | NPSR1 (0.42) | NPC1RAB9ASMN1; SMN2CYP2C19 | |
| SCHEMBL7093752 | 0.73 | TET3 (0.30) | TET3KMT2AFBXL19CXXC5TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236250-A1 | Cyclohexane derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LTD. (GB) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236250-A1 | Cyclohexane derivatives and their use as therapeutic agents | CNR2, CNR1, HTR1A | TEAD3 3989/4885TET3 4276/4885KMT2A 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.