Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057567 | 0.72 | THRB (0.38) | THRATHRB | |
| SCHEMBL7057569 | 0.72 | THRB (0.41) | THRATHRB | |
| SCHEMBL7025061 | 0.70 | THRA (0.60) | THRATHRB | |
| SCHEMBL7124400 | 0.68 | THRA (0.54) | THRATHRBALDH1A1 | |
| SCHEMBL3635237 | 0.65 | TSHR (0.54) | THRBALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL19762005 | 0.61 | ALDH1A1 (0.56) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31612527 | 0.61 | CYP2C19 (0.55) | HTTALDH1A1POLBTSHR | |
| SCHEMBL7449929 | 0.60 | GABRA1 (0.53) | THRATHRBALDH1A1MCL1 | |
| SCHEMBL14025237 | 0.57 | SLC6A2 (0.44) | ALDH1A1TSHR | |
| SCHEMBL921473 | 0.57 | ESR1 (0.52) | THRATHRBHTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |