Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL7035853 | 1.00 | — | — | |
| Fluoride Ion SCHEMBL62811 | 1.00 | — | — | |
| Fluoride SCHEMBL16824044 | 0.87 | — | — | |
| Fluoride SCHEMBL1949794 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL27280150 | 0.87 | — | — | |
| Potassium Ion SCHEMBL122678 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL6175 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL552564 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL10979901 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL3038547 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114689-A1 | 5-halo-4-fluoro-4,7,7-trimethyl-3-oxabicyclo[4.1.0]heptan-2-ones, process for their preparation and their use for preparing cyclopropanecarboxylic acids | DEMOUTE JEAN PIERRE (DE) | 2003-06-19 | — | — | US | disclosed |
| US-6498267-B2 | PREPARATION OF PYRETHROIDS. | AVENTIS CROPSCIENCE GMBH (DE) | 2002-12-24 | — | — | US | disclosed |
| EP-1230233-A1 | 5-HALO-4-FLUORO-4,7,7-TRIMETHYL-3-OXABICYCLO 4.1.0]HEPTANE-2-ONES, METHOD FOR THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF CYCLOPROPANE CARBOXYLIC ACIDS | Aventis CropScience GmbH (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-20020045766-A1 | 5-halo-4-fluoro-4,7,7-trimethyl-3-oxabicyclo[4.1.0]heptan-2-ones, process for their preparation and their use for preparing cyclopropanecarboxylic acids | DEMOUTE JEAN PIERRE (DE) | 2002-04-18 | — | — | US | disclosed |
| US-6337407-B1 | HALOGENATED COMPOUNDS WITH HETEROCYCLIC ESTER COMPOUNDS | AVENTIS CROPSCIENCE GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| WO-2001034592-A1 | 5-HALO-4-FLUORO-4,7,7-TRIMETHYL-3-OXABICYCLO[4.1.0]HEPTANE-2-ONES, METHOD FOR THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF CYCLOPROPANE CARBOXYLIC ACIDS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-05-17 | — | — | WO | disclosed |