Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | TEK | Q02763 | 3/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894991 | 0.89 | LOXL2 (0.43) | KDRPDGFRAMMP14AURKAMET | |
| SCHEMBL7062869 | 0.80 | TTR (0.39) | KDRPDGFRAMETGAARCE1 | |
| SCHEMBL29137432 | 0.78 | PDGFRA (0.69) | KDRPDGFRAPDGFRBAURKAMET | |
| SCHEMBL4849002 | 0.76 | GAA (0.47) | IDO1MMP14NPC1MAPTTSHR | |
| SCHEMBL17506817 | 0.75 | CYP3A4 (0.43) | MMP14MAPTRAB9AMMP2CYP3A4 | |
| SCHEMBL30040301 | 0.74 | NR4A1 (0.61) | HSP90AA1MMP14MAPTTSHRRAB9A | |
| SCHEMBL436522 | 0.74 | NR4A1 (0.61) | HSP90AA1MMP14MAPTTSHRRAB9A | |
| SCHEMBL17506790 | 0.74 | CYP3A4 (0.42) | MMP14MAPTTSHRRAB9AMMP2 | |
| SCHEMBL716943 | 0.73 | GAA (0.52) | MMP14NPC1MAPTTSHRRAB9A | |
| SCHEMBL2178592 | 0.72 | KDR (0.43) | KDRPDGFRAPDGFRBAURKAMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824949-B2 | SELF-CONDENSATION OF AN O-AMINOPHENOLCARBOXYLIC ACID AND REACTION WITH BIS-O-AMINOPHENOLS ALONG WITH DICARBOXYLIC ACID AND ACETYLENE COMPOUNDS; HIGH RESISTANCE AGAINST THE DIFFUSION OF METALS | INFINEON TECHNOLOGIES AG (DE) | 2004-11-30 | — | — | US | disclosed |
| US-6531632-B2 | Reacting dihydroxy compound with halogenated o-nitrophenol | INFINEON TECHNOLOGIES AG (DE) | 2003-03-11 | — | — | US | disclosed |
| US-20020086968-A1 | Polybenzoxazole precursors, photoresist solution, polybenzoxazole, and process for preparing a polybenzoxazole precursor | POLARIS INNOVATIONS LIMITED (IE) | 2002-07-04 | — | — | US | disclosed |
| EP-1189974-A1 | POLYBENZOXAZOLE PRECURSORS | Infineon Technologies AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-20020010370-A1 | Bis-o-aminophenols and o-aminophenolcarboxylic acids and process for preparing the same | POLARIS INNOVATIONS LIMITED (IE) | 2002-01-24 | — | — | US | disclosed |
| WO-2001066619-A1 | POLYBENZOXAZOLE PRECURSORS | INFINEON TECHNOLOGIES AG (DE) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132374-A2 | Bis-o-aminophenols and o-aminophenolcarboxylic acids | Infineon Technologies AG (DE) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010370-A1 | Bis-o-aminophenols and o-aminophenolcarboxylic acids and process for preparing the same | FOS, POF1B, FOSB | KDR 4474/4885PDGFRA 4452/4885PDGFRB 4645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.