Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067451 | 0.90 | GPR35 (0.42) | GPR35LMNAMAPTPTP4A1GABRA1 | |
| SCHEMBL447954 | 0.86 | MAPT (0.46) | GPR35LMNAMAPTPTP4A1GABRA1 | |
| SCHEMBL30004700 | 0.79 | THRB (0.35) | MAPTGABRA1GABRB1THRBTDP1 | |
| SCHEMBL448738 | 0.79 | THRB (0.35) | MAPTGABRA1GABRB1THRBTDP1 | |
| SCHEMBL7066987 | 0.77 | THRB (0.38) | LMNAMAPTTHRBTDP1THRA | |
| SCHEMBL1808553 | 0.75 | TSHR (0.45) | LMNAMAPTTHRBTDP1KDM4E | |
| SCHEMBL7063016 | 0.74 | ALOX5 (0.39) | GPR35LMNAMAPTTHRBKDM4E | |
| SCHEMBL7066169 | 0.74 | MAPT (0.34) | GPR35LMNAMAPTPTP4A1GABRA1 | |
| SCHEMBL7708397 | 0.72 | GABRA1 (0.35) | GABRA1GABRB1KMT2ATSHRPPARA | |
| SCHEMBL7061577 | 0.72 | GABRA1 (0.35) | GABRA1GABRB1THRBTHRAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | claimed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | claimed |
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-20020123590-A1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-05 | — | — | US | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6261700-B1 | HARD COATING | 3M INNOVATIVE PROPERTIES COMPANY | 2001-07-17 | — | — | US | disclosed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1105430-A1 | CERAMER CONTAINING A BROMINATED POLYMER AND INORGANIC OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |
| WO-2000006622-A1 | CERAMER CONTAINING A BROMINATED POLYMER AND INORGANIC OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123590-A1 | Brominated materials | PBRM1, TUBB3, TUBB | GPR35 3479/4885LMNA 1610/4885MAPT 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.