SCHEMBL7066213

SCHEMBL7066213

CC(OC(=O)C(CCOS(=O)(=O)c1ccccc1)OS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.38
RAB9A P51151 1/20 0.36
CHRM2 P08172 3/20 0.35
CHRM1 P11229 3/20 0.35
CHRM4 P08173 2/20 0.35
CHRM3 P20309 2/20 0.35
HSD11B1 P28845 1/20 0.33
S1PR5 Q9H228 2/20 0.33
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7065786 0.93 STAT3 (0.37) HCAR2
SCHEMBL7066495 0.89 RAB9A (0.39) RAB9A
SCHEMBL7067274 0.83 KMT2A (0.41) RAB9A
SCHEMBL7064394 0.82 HCAR2 (0.40) HCAR2CHRM2CHRM1CHRM4CHRM3
SCHEMBL7064430 0.82 TDP1 (0.42) RAB9ACHRM2CHRM1HSD11B1
SCHEMBL7971396 0.81 RAB9A (0.37) RAB9A
SCHEMBL7959970 0.81 RAB9A (0.36) RAB9A
SCHEMBL7060919 0.80 THRB (0.37) HSD11B1
SCHEMBL7065836 0.80 MAPT (0.41)
SCHEMBL7067159 0.79 TSHR (0.41) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed