SCHEMBL7065786

SCHEMBL7065786

Cc1ccc(S(=O)(=O)OCCC(OS(=O)(=O)c2ccc(C)cc2)C(=O)OC(C)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.37
PKM P14618 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
FKBP1A P62942 1/20 0.35
RECQL P46063 1/20 0.34
ALDH1A1 P00352 3/20 0.34
KCNA5 P22460 1/20 0.34
GPR139 Q6DWJ6 1/20 0.34
HPGD P15428 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066213 0.93 HCAR2 (0.38) HCAR2
SCHEMBL7064465 0.86 STAT3 (0.38) STAT3LMNAKMT2AALDH1A1GAA
SCHEMBL7060903 0.83 HTT (0.39) STAT3LMNAKMT2ARECQLALDH1A1
SCHEMBL7066495 0.82 RAB9A (0.39) MEN1KMT2AALDH1A1HPGDGAA
SCHEMBL7064562 0.82 LMNA (0.49) LMNAALDH1A1HPGD
SCHEMBL7065725 0.81 ALDH1A1 (0.42) STAT3LMNAMEN1KMT2AFKBP1A
SCHEMBL7064469 0.81 KMT2A (0.42) STAT3LMNAMEN1KMT2ARECQL
SCHEMBL7066596 0.81 STAT3 (0.42) STAT3PKMLMNAMEN1KMT2A
SCHEMBL7973217 0.79 PSMD10 (0.38) STAT3LMNAMEN1KMT2AALDH1A1
SCHEMBL7060919 0.79 THRB (0.37) PKMMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed