SCHEMBL7066495

SCHEMBL7066495

CC(C)OC(=O)C(CCOS(=O)(=O)c1ccccc1)OS(=O)(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.37
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
CYP2C19 P33261 1/20 0.34
FABP4 P15090 1/20 0.34
HPGD P15428 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7971396 0.92 RAB9A (0.37) RAB9ATSHRKMT2AALDH1A1GAA
SCHEMBL7959970 0.91 RAB9A (0.36) RAB9ATSHRKMT2AALDH1A1GAA
SCHEMBL7066213 0.89 HCAR2 (0.38) RAB9A
SCHEMBL7064465 0.88 STAT3 (0.38) RAB9AKMT2AALDH1A1GAACA12
SCHEMBL7067274 0.86 KMT2A (0.41) RAB9AKMT2AMEN1CA12CA2
SCHEMBL7064430 0.85 TDP1 (0.42) RAB9ATSHRKMT2AALDH1A1MEN1
SCHEMBL7065836 0.83 MAPT (0.41) CA2CA9
SCHEMBL7065786 0.82 STAT3 (0.37) KMT2AALDH1A1GAAMEN1HPGD
SCHEMBL7067159 0.82 TSHR (0.41) RAB9ATSHRALDH1A1
SCHEMBL7068104 0.82 ALDH1A1 (0.40) RAB9AKMT2AALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed