Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972978 | 0.92 | KMT2A (0.40) | KMT2AMEN1CA12CA2CA7 | |
| SCHEMBL7972944 | 0.91 | KMT2A (0.39) | KMT2AMEN1CA12CA2CA7 | |
| SCHEMBL7066596 | 0.88 | STAT3 (0.42) | KMT2AMEN1CA12CA9SMN1; SMN2 | |
| SCHEMBL7064430 | 0.88 | TDP1 (0.42) | KMT2AMEN1CA12CA2CA9 | |
| SCHEMBL7066495 | 0.86 | RAB9A (0.39) | KMT2AMEN1CA12CA2CA9 | |
| SCHEMBL7065836 | 0.85 | MAPT (0.41) | CA2CA9ATMSMN1; SMN2 | |
| SCHEMBL7067159 | 0.84 | TSHR (0.41) | NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL7068104 | 0.84 | ALDH1A1 (0.40) | KMT2ACA12CA2CA9NPC1 | |
| SCHEMBL10012441 | 0.83 | CA12 (0.44) | KMT2AMEN1CA12CA2CA7 | |
| SCHEMBL7066213 | 0.83 | HCAR2 (0.38) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |