Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071281 | 0.88 | LTA4H (0.50) | LTA4HCTSLCTSBCTSSCTSK | |
| SCHEMBL7068133 | 0.86 | MMP2 (0.46) | MMP3MMP2MMP1 | |
| SCHEMBL7135100 | 0.81 | MME (0.48) | MMP2MMP1MMEACECPA1 | |
| SCHEMBL7066975 | 0.80 | LTA4H (0.46) | LTA4HCTSLCTSBCTSSCTSK | |
| SCHEMBL7983227 | 0.69 | MMP1 (0.54) | MMP3MMP2MMP1MME | |
| SCHEMBL7068105 | 0.69 | EPHX2 (0.47) | NPC1MMELMNA | |
| SCHEMBL7068135 | 0.68 | MMP2 (0.51) | MMP3MMP2MMP1 | |
| SCHEMBL27549172 | 0.65 | MMP2 (0.58) | MMP3MMP2MMP1 | |
| SCHEMBL18127223 | 0.65 | GRN (0.69) | LTA4HCTSLCTSBCTSSCTSK | |
| SCHEMBL1083717 | 0.64 | HKDC1 (0.50) | KMT2AMMELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |
| EP-1060161-A1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999044989-A1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1999-09-10 | — | — | WO | disclosed |