Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.54 |
| ▸ | FCER2 | P06734 | 3/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 13/20 | 0.50 |
| ▸ | MMP2 | P08253 | 12/20 | 0.50 |
| ▸ | MMP7 | P09237 | 9/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135100 | 0.86 | MME (0.48) | MMP1FCER2MMEMMP2MMP8 | |
| SCHEMBL7071281 | 0.82 | LTA4H (0.50) | MMP1FCER2MMP3MMP2 | |
| SCHEMBL7073460 | 0.81 | MME (0.42) | MMP1FCER2MMEMMP3MMP2 | |
| SCHEMBL7068105 | 0.73 | EPHX2 (0.47) | MME | |
| SCHEMBL8664100 | 0.72 | MMP2 (0.49) | MMP1FCER2MMP3MMP2MMP9 | |
| SCHEMBL20322875 | 0.70 | MMP1 (0.77) | MMP1FCER2MMP3MMP2MMP7 | |
| SCHEMBL20322878 | 0.70 | MMP1 (0.77) | MMP1FCER2MMP3MMP2MMP7 | |
| SCHEMBL7128547 | 0.70 | MME (0.51) | MME | |
| SCHEMBL7128546 | 0.70 | MME (0.51) | MME | |
| SCHEMBL4813526 | 0.69 | MMP3 (0.83) | MMP1FCER2MMP3MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |