Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987826 | 0.79 | KDM4E (0.37) | CYP1A2CYP2A6CYP1A1CYP1B1KDM4E | |
| SCHEMBL6655477 | 0.79 | MAOA (0.42) | CYP1A2CYP2A6CYP3A4CYP2C19KDM4E | |
| SCHEMBL8528792 | 0.79 | ALDH1A1 (0.44) | CYP1A2CYP2A6HDAC8CYP3A4CYP2D6 | |
| SCHEMBL8125196 | 0.79 | CYP1A2 (0.40) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5670544 | 0.78 | MEN1 (0.40) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8123605 | 0.78 | RAB9A (0.46) | CYP1A2CYP2A6CYP11B1RAB9AMAPT | |
| SCHEMBL2452946 | 0.77 | MCL1 (0.46) | HDAC8MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8125457 | 0.76 | ACHE (0.39) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7722881 | 0.76 | ESR1 (0.43) | CYP1A2CYP11B1CYP11B2CYP3A4CYP17A1 | |
| SCHEMBL15066961 | 0.75 | ALDH1A1 (0.41) | CYP1A2CYP2A6CYP3A4CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159623-C | Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent | 克拉瑞特金融(BVI)有限公司 | 2004-07-28 | — | — | CN | disclosed |
| EP-1313747-A1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | Basell Polypropylen GmbH (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018397-A1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYPROPYLEN GMBH (DE) | 2002-03-07 | — | — | WO | disclosed |
| CN-1274433-A | Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent | CLARIANT INT LTD (CH) | 2000-11-22 | — | — | CN | disclosed |
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-4892887-A | ANTITUMOR | YALE UNIVERSITY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4684747-A | ANTITUMOR, ALKYLATING AGENTS | YALE UNIVERSITY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0083312-A1 | Aqueous based fire foam compositions containing hydrocarbyl sulfide terminated oligomer stabilizers | CIBA-GEIGY AG (CH) | 1983-07-06 | — | — | EP | disclosed |