Sugi Predict

Sugi Predict / Compounds / SCHEMBL7069810

SCHEMBL7069810

SCHEMBL7069810

COc1ccc(CO[C@@H](C)C=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 3/20 0.48
▸ AGXT P21549 2/20 0.48
▸ SLC6A4 P31645 1/20 0.46
▸ NPC1 O15118 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ APP P05067 3/20 0.43
▸ HTT P42858 2/20 0.43
▸ LDHA P00338 1/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ ALOX12 P18054 1/20 0.43
▸ FFAR1 O14842 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ CYP2A6 P11509 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16594094 1.00 IDO1 (0.48) IDO1AGXTSLC6A4NPC1RAB9A
SCHEMBL14567490 0.83 NPC1 (0.47) IDO1AGXTSLC6A4NPC1RAB9A
SCHEMBL6239311 0.79 SLC1A3 (0.47) IDO1AGXTALDH1A1TSHR
SCHEMBL4588952 0.79 SLC1A3 (0.47) IDO1AGXTALDH1A1TSHR
SCHEMBL6172748 0.79 SLC1A3 (0.47) IDO1AGXTALDH1A1TSHR
SCHEMBL12502485 0.79 IDO1 (0.53) IDO1AGXTSLC6A4NPC1RAB9A
SCHEMBL21996211 0.79 IDO1 (0.46) IDO1AGXTSLC6A4NPC1RAB9A
SCHEMBL12772124 0.79 IDO1 (0.46) IDO1AGXTSLC6A4NPC1RAB9A
SCHEMBL2610461 0.79 IDO1 (0.57) IDO1AGXTSLC6A4APP
SCHEMBL6884424 0.78 SMN1; SMN2 (0.47) IDO1AGXTNPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107426999-B Pyridine amide compounds having fungicidal activity 美国陶氏益农公司 2023-01-20 — — CN disclosed
CN-107205399-B Picolinamides as fungicides 美国陶氏益农公司 2021-01-29 — — CN disclosed
EP-3255991-B1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2020-09-30 — — EP disclosed
EP-3240413-B1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2020-05-13 — — EP disclosed
US-10433555-B2 Picolinamide compounds with fungicidal activity DOW AGROSCIENCES LLC (US) 2019-10-08 — — US disclosed
US-10173981-B2 Picolinamides as fungicides DOW AGROSCIENCES LLC (US) 2019-01-08 — — US disclosed
US-20180000080-A1 PICOLINAMIDES AS FUNGICIDES CORTEVA AGRISCIENCE LLC 2018-01-04 — — US disclosed
US-20180000075-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC 2018-01-04 — — US disclosed
US-20180000085-A1 USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC 2018-01-04 — — US disclosed
US-20180002288-A1 USE OF PICOLINAMIDES AS FUNGICIDES CORTEVA AGRISCIENCE LLC 2018-01-04 — — US disclosed
WO-2016109305-A1 USE OF PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed
WO-2016109305-A1 USE OF PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed
WO-2016109304-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed
WO-2016109288-A1 USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed
WO-2016109304-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2016-07-07 — — WO disclosed
US-9265253-B2 Use of macrocyclic picolinamides as fungicides DOW AGROSCIENCES LLC (US) 2016-02-23 — — US disclosed
US-20150094281-A1 USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC 2015-04-02 — — US disclosed
US-20150094341-A1 MACROCYCLIC PICOLINAMIDES COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC 2015-04-02 — — US disclosed
US-20030134883-A1 14-Methyl-epothilones KOSAN BIOSCIENCES,INC. 2003-07-17 — — US disclosed
WO-2003045324-A2 14-METHYL-EPOTHILONES KOSAN BIOSCIENCES, INC. (US) 2003-06-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150094341-A1 MACROCYCLIC PICOLINAMIDES COMPOUNDS WITH FUNGICIDAL ACTIVITY FKBP14, CYP51A1, FKBP2 IDO1 398/4885AGXT 792/4885SLC6A4 3719/4885
US-20030134883-A1 14-Methyl-epothilones DNMT1, TET1, MYC IDO1 3539/4885AGXT 3850/4885SLC6A4 4536/4885
US-20180000075-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY PFAS, CASP2, CYP1A2 IDO1 1393/4885AGXT 972/4885SLC6A4 2413/4885
US-10433555-B2 Picolinamide compounds with fungicidal activity PFAS, CASP2, CYP1A2 IDO1 1393/4885AGXT 972/4885SLC6A4 2413/4885
US-20180000080-A1 PICOLINAMIDES AS FUNGICIDES CYP1A2, CYP4F12, FKBP2 IDO1 582/4885AGXT 801/4885SLC6A4 1821/4885
US-20150094281-A1 USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES FKBP14, CYP4F12, CYP1A2 IDO1 1000/4885AGXT 647/4885SLC6A4 2486/4885
US-20180002288-A1 USE OF PICOLINAMIDES AS FUNGICIDES PFAS, CYP1A2, CYP4F12 IDO1 875/4885AGXT 767/4885SLC6A4 1772/4885
US-10173981-B2 Picolinamides as fungicides CYP1A2, CYP4F12, FKBP2 IDO1 582/4885AGXT 801/4885SLC6A4 1821/4885
US-20180000085-A1 USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY PFAS, CYP1A2, CYP51A1 IDO1 1491/4885AGXT 946/4885SLC6A4 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.