Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 13/20 | 0.47 |
| ▸ | MMP1 | P03956 | 10/20 | 0.47 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MMP9 | P14780 | 6/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072801 | 0.74 | MMP2 (0.56) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL7073422 | 0.74 | MMP2 (0.50) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL7068205 | 0.70 | MMP3 (0.47) | MMP3MMP1MMP2 | |
| SCHEMBL9067396 | 0.67 | MMP1 (0.51) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL9284470 | 0.65 | MMP2 (1.00) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL21008679 | 0.65 | LTA4H (0.56) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL7980261 | 0.63 | MMP2 (0.57) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL8872686 | 0.63 | MMP2 (0.76) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL219929 | 0.62 | LTA4H (1.00) | MMP3MMP1MMP2MMP9MMP14 | |
| SCHEMBL219930 | 0.62 | LTA4H (1.00) | MMP3MMP1MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |