Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069936 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL7069359 | 0.89 | THRB (0.48) | SMN1; SMN2KMT2AMEN1LMNAATM | |
| SCHEMBL7074664 | 0.87 | THRB (0.53) | SMN1; SMN2KMT2AMEN1LMNAATM | |
| SCHEMBL7073993 | 0.86 | ALDH1A1 (0.60) | SMN1; SMN2KMT2AMEN1LMNAMGLL | |
| SCHEMBL8072947 | 0.85 | THRB (0.46) | SMN1; SMN2KMT2AMEN1LMNAATM | |
| SCHEMBL7071746 | 0.85 | MEN1 (0.54) | SMN1; SMN2KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL8073643 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2KMT2ALMNAMGLL | |
| SCHEMBL7070562 | 0.84 | F10 (0.57) | ATM | |
| SCHEMBL7071596 | 0.83 | LMNA (0.54) | SMN1; SMN2KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL7074222 | 0.83 | LMNA (0.62) | SMN1; SMN2KMT2AMEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |