Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | HTR6 | P50406 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ADK | P55263 | 5/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070066 | 0.82 | ADK (0.79) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL7074340 | 0.79 | SIGMAR1 (0.83) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL7077466 | 0.79 | HTR2B (0.69) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL7077959 | 0.78 | SIGMAR1 (0.81) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL7070318 | 0.77 | HTR2B (0.69) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL8331212 | 0.77 | ADK (0.71) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL15477884 | 0.76 | METTL3 (0.79) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL15570446 | 0.76 | METTL3 (0.79) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL16941466 | 0.76 | METTL3 (0.79) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C | |
| SCHEMBL8332977 | 0.75 | ADORA3 (0.69) | HTR2BSIGMAR1TMEM97OPRK1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051899-A1 | DEAZAPURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |