Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 9/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.33 |
| ▸ | RASGRP3 | Q8IV61 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RASGRP1 | O95267 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070815 | 0.89 | PRKCA (0.37) | PRKCAPRKCERASGRP3PRKCD | |
| SCHEMBL7070705 | 0.86 | HSD11B1 (0.32) | TSHR | |
| SCHEMBL5385910 | 0.78 | IDH1 (0.34) | — | |
| SCHEMBL4952252 | 0.76 | SMN1; SMN2 (0.38) | PRKCAPRKCESMN1; SMN2 | |
| SCHEMBL4952249 | 0.76 | SMN1; SMN2 (0.38) | PRKCAPRKCERASGRP3SMN1; SMN2 | |
| SCHEMBL7073820 | 0.71 | ELANE (0.30) | — | |
| SCHEMBL5389794 | 0.70 | IDH1 (0.33) | — | |
| SCHEMBL7070371 | 0.69 | IDH1 (0.34) | — | |
| SCHEMBL12059177 | 0.69 | PRKCA (0.39) | PRKCAPRKCERASGRP3PRKCDSMN1; SMN2 | |
| SCHEMBL7670571 | 0.69 | ALDH1A1 (0.34) | PRKCAPRKCERASGRP3NPC1RASGRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664353-B2 | Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-16 | — | — | US | disclosed |
| US-20030125494-A1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |