Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385910 | 0.89 | IDH1 (0.34) | HSD11B1HTR7 | |
| SCHEMBL7070697 | 0.86 | TSHR (0.34) | TSHR | |
| SCHEMBL5389794 | 0.79 | IDH1 (0.33) | HSD11B1 | |
| SCHEMBL7070371 | 0.79 | IDH1 (0.34) | HSD11B1HTR7 | |
| SCHEMBL7070815 | 0.79 | PRKCA (0.37) | — | |
| SCHEMBL5396081 | 0.76 | MITF (0.34) | HSD11B1 | |
| SCHEMBL7073820 | 0.76 | ELANE (0.30) | ELANE | |
| SCHEMBL27677901 | 0.75 | S1PR5 (0.31) | — | |
| SCHEMBL5396442 | 0.75 | IDH1 (0.37) | HSD11B1TSHR | |
| SCHEMBL5401519 | 0.74 | OPRM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664353-B2 | Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-16 | — | — | US | disclosed |
| US-20030125494-A1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6479608-B1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-12 | — | — | US | disclosed |