Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 3/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.30 |
| ▸ | MMP13 | P45452 | 2/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070371 | 0.87 | IDH1 (0.34) | CTSKCTSVCTSLCTSSIDH1 | |
| SCHEMBL5389794 | 0.83 | IDH1 (0.33) | CTSKCTSVCTSLCTSSIDH1 | |
| SCHEMBL5385910 | 0.82 | IDH1 (0.34) | CTSKCTSVCTSLCTSSIDH1 | |
| SCHEMBL5396442 | 0.80 | IDH1 (0.37) | IDH1 | |
| SCHEMBL13562989 | 0.79 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL5396081 | 0.77 | MITF (0.34) | OPRM1OPRD1OPRK1OPRL1CTSK | |
| SCHEMBL5402085 | 0.76 | IDH1 (0.35) | OPRM1OPRD1OPRK1OPRL1IDH1 | |
| SCHEMBL5391659 | 0.75 | IDH1 (0.34) | OPRM1OPRD1IDH1 | |
| SCHEMBL5402134 | 0.75 | IDH1 (0.34) | OPRM1OPRD1IDH1 | |
| SCHEMBL7070705 | 0.74 | HSD11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1481012-B1 | OPEN-CHAIN ALKOXYAMINES AND THEIR CORRESPONDING NITROXIDES FOR CONTROLLED LOW TEMPERATURE RADICAL POLYMERIZATION | CIBA SC HOLDING AG (CH) | 2006-05-17 | — | — | EP | disclosed |
| US-20050124814-A1 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124814-A1 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | ALOX5, NOS2, NOS1 | OPRM1 54/4885OPRD1 99/4885OPRK1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.